Molecular Cancer Therapeutics
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Contents: May 1 2005, Volume 4, Issue 5   [Index by Author] 
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Articles:

The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3)
Frank G. Bottone, Jr., Yuseok Moon, Jong Sik Kim, Brenda Alston-Mills, Minako Ishibashi, and Thomas E. Eling
Mol Cancer Ther 2005 4: 693-703. [Abstract] [Full Text] [PDF]  

N-glycosylation and microtubule integrity are involved in apical targeting of prostate-specific membrane antigen: implications for immunotherapy
Jason J. Christiansen, Sigrid A. Rajasekaran, Landon Inge, Lirong Cheng, Gopalakrishnapillai Anilkumar, Neil H. Bander, and Ayyappan K. Rajasekaran
Mol Cancer Ther 2005 4: 704-714. [Abstract] [Full Text] [PDF]  

Circulating plasma vascular endothelial growth factor in mice bearing human ovarian carcinoma xenograft correlates with tumor progression and response to therapy
Luigi Manenti, Elena Riccardi, Sergio Marchini, Elitza Naumova, Irene Floriani, Angela Garofalo, Romina Dossi, Eleonora Marrazzo, Domenico Ribatti, Eugenio Scanziani, MariaRosa Bani, Dorina Belotti, Massimo Broggini, and Raffaella Giavazzi
Mol Cancer Ther 2005 4: 715-725. [Abstract] [Full Text] [PDF]  

Protein kinase C-{alpha} mediates epidermal growth factor receptor transactivation in human prostate cancer cells
Jubilee R. Stewart and Catherine A. O'Brian
Mol Cancer Ther 2005 4: 726-732. [Abstract] [Full Text] [PDF]  

Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death
Lori Emert-Sedlak, Sanjeev Shangary, Asaf Rabinovitz, Michelle B. Miranda, Scott M. Delach, and Daniel E. Johnson
Mol Cancer Ther 2005 4: 733-742. [Abstract] [Full Text] [PDF]  

Overexpression of hRFI (human ring finger homologous to inhibitor of apoptosis protein type) inhibits death receptor–mediated apoptosis in colorectal cancer cells
Tsuyoshi Konishi, Shin Sasaki, Toshiaki Watanabe, Joji Kitayama, and Hirokazu Nagawa
Mol Cancer Ther 2005 4: 743-750. [Abstract] [Full Text] [PDF]  

Matrix metalloproteinase–activated doxorubicin prodrugs inhibit HT1080 xenograft growth better than doxorubicin with less toxicity
Charles F. Albright, Nilsa Graciani, Wei Han, Eddy Yue, Ross Stein, Zhihong Lai, Melody Diamond, Randine Dowling, Lisa Grimminger, Shu-Yun Zhang, Davette Behrens, Amy Musselman, Robert Bruckner, Mingzhu Zhang, Xiang Jiang, Daniel Hu, Anne Higley, Susan DiMeo, Maria Rafalski, Sandya Mandlekar, Bruce Car, Swamy Yeleswaram, Andrew Stern, Robert A. Copeland, Andrew Combs, Steve P. Seitz, George L. Trainor, Rebecca Taub, Pearl Huang, and Allen Oliff
Mol Cancer Ther 2005 4: 751-760. [Abstract] [Full Text] [PDF]  

The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach
Katayoun A. Jessen, Nicole M. English, Jean Yu Wang, Sergei Maliartchouk, Shannon P. Archer, Ling Qiu, Regina Brand, Jared Kuemmerle, Han-Zhong Zhang, Kurt Gehlsen, John Drewe, Ben Tseng, Sui Xiong Cai, and Shailaja Kasibhatla
Mol Cancer Ther 2005 4: 761-771. [Abstract] [Full Text] [PDF] Supplementary Data  

Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions
Lianne M. McHardy, Kaoru Warabi, Raymond J. Andersen, Calvin D. Roskelley, and Michel Roberge
Mol Cancer Ther 2005 4: 772-778. [Abstract] [Full Text] [PDF]  

Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis
Roberto Tonelli, Stefania Purgato, Consuelo Camerin, Raffaele Fronza, Fabrizio Bologna, Simone Alboresi, Monica Franzoni, Roberto Corradini, Stefano Sforza, Andrea Faccini, Jason M. Shohet, Rosangela Marchelli, and Andrea Pession
Mol Cancer Ther 2005 4: 779-786. [Abstract] [Full Text] [PDF]  

Fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma
Lijun Zhu, George Somlo, Bingsen Zhou, Jimin Shao, Victoria Bedell, Marilyn L. Slovak, Xiyong Liu, Jianhong Luo, and Yun Yen
Mol Cancer Ther 2005 4: 787-798. [Abstract] [Full Text] [PDF]  

The role of IFN regulatory factor-3 in the cytotoxic activity of NS-9, a polyinosinic-polycytidylic acid/cationic liposome complex, against tumor cells
Tomonori Uno, Kazuko Hirabayashi, Masatoshi Murai, Junichi Yano, and Keiko Ozato
Mol Cancer Ther 2005 4: 799-805. [Abstract] [Full Text] [PDF]  

Identification of novel targeting peptides for human ovarian cancer cells using "one-bead one-compound" combinatorial libraries
Olulanu H. Aina, Jan Marik, Ruiwu Liu, Derick H. Lau, and Kit S. Lam
Mol Cancer Ther 2005 4: 806-813. [Abstract] [Full Text] [PDF]  

Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naïve patients
Nerea Martínez, Margarita Sánchez-Beato, Amancio Carnero, Victoria Moneo, Juan C. Tercero, Isabel Fernández, Mercedes Navarrete, José Jimeno, and Miguel A. Piris
Mol Cancer Ther 2005 4: 814-823. [Abstract] [Full Text] [PDF]  

The selective retinoid X receptor agonist bexarotene (LGD1069, Targretin) prevents and overcomes multidrug resistance in advanced breast carcinoma
Wan-Ching Yen and William W. Lamph
Mol Cancer Ther 2005 4: 824-834. [Abstract] [Full Text] [PDF]  

Human mesothelioma cells exhibit tumor cell–specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase
Maria E. Ramos-Nino, Giovina Vianale, Tara Sabo-Attwood, Luciano Mutti, Camilo Porta, Nicholas Heintz, and Brooke T. Mossman
Mol Cancer Ther 2005 4: 835-842. [Abstract] [Full Text] [PDF]  

Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors
Rami G. Azrak, Jinsheng Yu, Lakshmi Pendyala, Patrick F. Smith, Shousong Cao, Xia Li, William D. Shannon, Farukh A. Durrani, Howard L. McLeod, and Youcef M. Rustum
Mol Cancer Ther 2005 4: 843-854. [Abstract] [Full Text] [PDF]  

The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
Susan Pratt, Robert L. Shepard, Ramani A. Kandasamy, Paul A. Johnston, William Perry, III, and Anne H. Dantzig
Mol Cancer Ther 2005 4: 855-863. [Abstract] [Full Text] [PDF]  

Correction:

Article on human copper transporter Ctr1 and cisplatin

Mol Cancer Ther 2005 4: 864. [Full Text] [PDF]  

Article on G3139 and Bcl-2-independent apoptosis in melanoma cells

Mol Cancer Ther 2005 4: 864. [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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Copyright © 2005 by the American Association for Cancer Research.