Articles:

Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16

Gregory N. Fuller, Xiaohua Su, Roger E. Price, Zvi R. Cohen, Frederick F. Lang, Raymond Sawaya, and Sadhan Majumder
Mol Cancer Ther 2005 4: 343-349. [Abstract] [Full Text] [PDF]  

Abrogation of fibroblast activation protein enzymatic activity attenuates tumor growth

Jonathan D. Cheng, Matthildi Valianou, Adrian A. Canutescu, Eileen K. Jaffe, Hyung-Ok Lee, Hao Wang, Jack H. Lai, William W. Bachovchin, and Louis M. Weiner
Mol Cancer Ther 2005 4: 351-360. [Abstract] [Full Text] [PDF]  

Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells

Josephine M. Atienza, Richard B. Roth, Caridad Rosette, Kevin J. Smylie, Stefan Kammerer, Joachim Rehbock, Jonas Ekblom, and Mikhail F. Denissenko
Mol Cancer Ther 2005 4: 361-368. [Abstract] [Full Text] [PDF]  

Targeting the platelet-derived growth factor receptor with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: Implications as a potential therapeutic target

Nick Loizos, Yan Xu, Jim Huber, Meilin Liu, Dan Lu, Bridget Finnerty, Robin Rolser, Asra Malikzay, Anita Persaud, Erik Corcoran, Dhanvanthri S. Deevi, Paul Balderes, Rajiv Bassi, Xenia Jimenez, Christopher J. Joynes, Venkata R.M. Mangalampalli, Philipp Steiner, James R. Tonra, Yan Wu, Daniel S. Pereira, Zhenping Zhu, Dale L. Ludwig, Daniel J. Hicklin, Peter Bohlen, Larry Witte, and Paul Kussie
Mol Cancer Ther 2005 4: 369-379. [Abstract] [Full Text] [PDF]  

Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells

Lijuan Xia, Duo Chen, Rui Han, Qicheng Fang, Samuel Waxman, and Yongkui Jing
Mol Cancer Ther 2005 4: 381-388. [Abstract] [Full Text] [PDF]  

Gene expression profiling revealed novel molecular targets of docetaxel and estramustine combination treatment in prostate cancer cells

Yiwei Li, Xin Hong, Maha Hussain, Sarah H. Sarkar, Ran Li, and Fazlul H. Sarkar
Mol Cancer Ther 2005 4: 389-398. [Abstract] [Full Text] [PDF]  

Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays

Noriyuki Nakatsu, Yoko Yoshida, Kanami Yamazaki, Tomoki Nakamura, Shingo Dan, Yasuhisa Fukui, and Takao Yamori
Mol Cancer Ther 2005 4: 399-412. [Abstract] [Full Text] [PDF]  

Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling

James S. Hardwick, Yi Yang, Chunsheng Zhang, Bin Shi, Rosemary McFall, Elizabeth J. Koury, Susan L. Hill, Hongyue Dai, Robert Wasserman, Robert L. Phillips, Edward J. Weinstein, Nancy E. Kohl, Michael E. Severino, John R. Lamb, and Laura Sepp-Lorenzino
Mol Cancer Ther 2005 4: 413-425. [Abstract] [Full Text] [PDF] Supplementary Data  

A recombinant, fully human, bispecific antibody neutralizes the biological activities mediated by both vascular endothelial growth factor receptors 2 and 3

Xenia Jimenez, Dan Lu, Laura Brennan, Kris Persaud, Meilin Liu, Huaquan Miao, Larry Witte, and Zhenping Zhu
Mol Cancer Ther 2005 4: 427-434. [Abstract] [Full Text] [PDF]  

Epidermal growth factor receptor (EGFR)–related protein inhibits multiple members of the EGFR family in colon and breast cancer cells

Hu Xu, Yingjie Yu, Dorota Marciniak, Arun K. Rishi, Fazlul H. Sarkar, Omer Kucuk, and Adhip P.N. Majumdar
Mol Cancer Ther 2005 4: 435-442. [Abstract] [Full Text] [PDF]  

The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim

Malti Nikrad, Thomas Johnson, Hamsa Puthalalath, Leigh Coultas, Jerry Adams, and Andrew S. Kraft
Mol Cancer Ther 2005 4: 443-449. [Abstract] [Full Text] [PDF]  

Bcl-XL small interfering RNA suppresses the proliferation of 5-fluorouracil-resistant human colon cancer cells

Hongbo Zhu, Wei Guo, Lidong Zhang, John J. Davis, Fuminori Teraishi, Shuhong Wu, Xiaobo Cao, Jonathan Daniel, W. Roy Smythe, and Bingliang Fang
Mol Cancer Ther 2005 4: 451-456. [Abstract] [Full Text] [PDF]  

Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways

Michael Hahn, Weiqun Li, Chunrong Yu, Mohamed Rahmani, Paul Dent, and Steven Grant
Mol Cancer Ther 2005 4: 457-470. [Abstract] [Full Text] [PDF]  

Small interfering RNA targeting of S phase kinase–interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation

Yasusei Kudo, Shojiro Kitajima, Ikuko Ogawa, Masae Kitagawa, Mutsumi Miyauchi, and Takashi Takata
Mol Cancer Ther 2005 4: 471-476. [Abstract] [Full Text] [PDF]  

Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARß2 in breast cancer cells

Nigel P. Mongan and Lorraine J. Gudas
Mol Cancer Ther 2005 4: 477-486. [Abstract] [Full Text] [PDF]  

The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15

Jong-Sik Kim, Seung Joon Baek, Tina Sali, and Thomas E. Eling
Mol Cancer Ther 2005 4: 487-493. [Abstract] [Full Text] [PDF]  

Minireview:

Imatinib and gastrointestinal stromal tumors: Where do we go from here?

Ugo De Giorgi and Jaap Verweij
Mol Cancer Ther 2005 4: 495-501. [Abstract] [Full Text] [PDF]  

Correction:

Article on roscovitine and P-Ser-46-p53

Mol Cancer Ther 2005 4: 503. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.