Articles:

Targeting stathmin in prostate cancer

Sucharita J. Mistry, Alexander Bank, and George F. Atweh
Mol Cancer Ther 2005 4: 1821-1829 doi: 10.1158/1535-7163.MCT-05-0215 [Abstract] [Full Text] [PDF]  

A dityrosyl-diiron radical cofactor center is essential for human ribonucleotide reductases

Bingsen Zhou, Jimin Shao, Leila Su, Yate-Ching Yuan, Christina Qi, Jennifer Shih, Bixin Xi, Bernard Chu, and Yun Yen
Mol Cancer Ther 2005 4: 1830-1836 doi: 10.1158/1535-7163.MCT-05-0273 [Abstract] [Full Text] [PDF]  

Knockdown of the cytoprotective chaperone, clusterin, chemosensitizes human breast cancer cells both in vitro and in vivo

Alan So, Shannon Sinnemann, David Huntsman, Ladan Fazli, and Martin Gleave
Mol Cancer Ther 2005 4: 1837-1849 doi: 10.1158/1535-7163.MCT-05-0178 [Abstract] [Full Text] [PDF]  

Transcriptional targeting modalities in breast cancer gene therapy using adenovirus vectors controlled by -lactalbumin promoter

Xiong Li, Jie Zhang, Huanling Gao, Edyta Vieth, Kyung-Hee Bae, Yan-Ping Zhang, Sang-Jin Lee, Sudhanshu Raikwar, Thomas A. Gardner, Gary D. Hutchins, Dale VanderPutten, Chinghai Kao, and Meei-Huey Jeng
Mol Cancer Ther 2005 4: 1850-1859 doi: 10.1158/1535-7163.MCT-05-0167 [Abstract] [Full Text] [PDF]  

Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers

Collins A. Karikari, Michael Mullendore, James R. Eshleman, Pedram Argani, Lorenzo M. Leoni, Shrikanta Chattopadhyay, Manuel Hidalgo, and Anirban Maitra
Mol Cancer Ther 2005 4: 1860-1866 doi: 10.1158/1535-7163.MCT-05-0103 [Abstract] [Full Text] [PDF]  

Transcript profiling in peripheral T-cell lymphoma, not otherwise specified, and diffuse large B-cell lymphoma identifies distinct tumor profile signatures

Daruka Mahadevan, Catherine Spier, Kimiko Della Croce, Susan Miller, Benjamin George, Chris Riley, Stephen Warner, Thomas M. Grogan, and Thomas P. Miller
Mol Cancer Ther 2005 4: 1867-1879 doi: 10.1158/1535-7163.MCT-05-0146 [Abstract] [Full Text] [PDF]  

Sensitization of DNA damage–induced apoptosis by the proteasome inhibitor PS-341 is p53 dependent and involves target proteins 14-3-3 and survivin

Susan A.J. Vaziri, Jason Hill, Kenichi Chikamori, Dale R. Grabowski, Nagio Takigawa, Mamta Chawla-Sarkar, Lisa R. Rybicki, Andrei V. Gudkov, Tarek Mekhail, Ronald M. Bukowski, Mahrukh K. Ganapathi, and Ram Ganapathi
Mol Cancer Ther 2005 4: 1880-1890 doi: 10.1158/1535-7163.MCT-05-0222 [Abstract] [Full Text] [PDF]  

Regulation of signaling phosphoproteins by epidermal growth factor and Iressa (ZD1839) in human endometrial cancer cells that model type I and II tumors

Lina Albitar, Laura L. Laidler, Rony Abdallah, and Kimberly K. Leslie
Mol Cancer Ther 2005 4: 1891-1899 doi: 10.1158/1535-7163.MCT-05-0274 [Abstract] [Full Text] [PDF]  

AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes

Justin M. Summy, Jose G. Trevino, Donald P. Lesslie, Cheryl H. Baker, William C. Shakespeare, Yihan Wang, Raji Sundaramoorthi, Chester A. Metcalf, III, Jeffrey A. Keats, Tomi K. Sawyer, and Gary E. Gallick
Mol Cancer Ther 2005 4: 1900-1911 doi: 10.1158/1535-7163.MCT-05-0171 [Abstract] [Full Text] [PDF]  

Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, and CMYC

Xiao-Nan Li, Qin Shu, Jack Men-Feng Su, Laszlo Perlaky, Susan M. Blaney, and Ching C. Lau
Mol Cancer Ther 2005 4: 1912-1922 doi: 10.1158/1535-7163.MCT-05-0184 [Abstract] [Full Text] [PDF]  

Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor

Sun Yang, Kaikobad Irani, Susan E. Heffron, Frances Jurnak, and Frank L. Meyskens, Jr.
Mol Cancer Ther 2005 4: 1923-1935 doi: 10.1158/1535-7163.MCT-05-0229 [Abstract] [Full Text] [PDF]  

Zinc ribbon domain-containing 1 (ZNRD1) mediates multidrug resistance of leukemia cells through regulation of P-glycoprotein and Bcl-2

Liu Hong, Ying Piao, Yu Han, Jun Wang, Xiaoyin Zhang, Yulei Du, Shanshan Cao, Taidong Qiao, Zhen Chen, and Daiming Fan
Mol Cancer Ther 2005 4: 1936-1942 doi: 10.1158/1535-7163.MCT-05-0182 [Abstract] [Full Text] [PDF]  

Simultaneous targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways for pancreatic cancer therapy

Shadan Ali, Basil F. El-Rayes, Fazlul H. Sarkar, and Philip A. Philip
Mol Cancer Ther 2005 4: 1943-1951 doi: 10.1158/1535-7163.MCT-05-0065 [Abstract] [Full Text] [PDF]  

Butyric acid prodrugs are histone deacetylase inhibitors that show antineoplastic activity and radiosensitizing capacity in the treatment of malignant gliomas

Michal Entin-Meer, Ada Rephaeli, Xiaodong Yang, Abraham Nudelman, Scott R. VandenBerg, and Daphne Adele Haas-Kogan
Mol Cancer Ther 2005 4: 1952-1961 doi: 10.1158/1535-7163.MCT-05-0087 [Abstract] [Full Text] [PDF]  

Response of endothelial cells to a dual tyrosine kinase receptor inhibition combined with irradiation

Alexandre Bozec, Patricia Formento, Joseph Ciccolini, Raphaëlle Fanciullino, Laetitia Padovani, Xavier Murraciole, Jean-Louis Fischel, and Gerard Milano
Mol Cancer Ther 2005 4: 1962-1971 doi: 10.1158/1535-7163.MCT-05-0108 [Abstract] [Full Text] [PDF]  

Down-regulation of c-FLIP contributes to the sensitization effect of 3,3'-diindolylmethane on TRAIL-induced apoptosis in cancer cells

Siyuan Zhang, Han-Ming Shen, and Choon Nam Ong
Mol Cancer Ther 2005 4: 1972-1981 doi: 10.1158/1535-7163.MCT-05-0249 [Abstract] [Full Text] [PDF]  

Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure

Ismael Samudio, Marina Konopleva, Stephen Safe, Teresa McQueen, and Michael Andreeff
Mol Cancer Ther 2005 4: 1982-1992 doi: 10.1158/1535-7163.MCT-05-0247 [Abstract] [Full Text] [PDF]  

In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates

Douglas C. Marchion, Elona Bicaku, Adil I. Daud, Daniel M. Sullivan, and Pamela N. Munster
Mol Cancer Ther 2005 4: 1993-2000 doi: 10.1158/1535-7163.MCT-05-0194 [Abstract] [Full Text] [PDF]  

Class III ß-tubulin expression in tumor cells predicts response and outcome in patients with non–small cell lung cancer receiving paclitaxel

Pascal Sève, John Mackey, Sylvie Isaac, Olivier Trédan, Pierre-Jean Souquet, Maurice Pérol, Raymond Lai, Alain Voloch, and Charles Dumontet
Mol Cancer Ther 2005 4: 2001-2007 doi: 10.1158/1535-7163.MCT-05-0244 [Abstract] [Full Text] [PDF]  

Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val⁶⁵⁴Ala

Sean R. McLean, Mali Gana-Weisz, Basil Hartzoulakis, Richard Frow, Jeremy Whelan, David Selwood, and Chris Boshoff
Mol Cancer Ther 2005 4: 2008-2015 doi: 10.1158/1535-7163.MCT-05-0070 [Abstract] [Full Text] [PDF]  

Cross-talk between DNA damage and cell survival checkpoints during G₂ and mitosis: pharmacologic implications

Przemyslaw Bozko, Michal Sabisz, Annette K. Larsen, and Andrzej Skladanowski
Mol Cancer Ther 2005 4: 2016-2025 doi: 10.1158/1535-7163.MCT-05-0138 [Abstract] [Full Text] [PDF]  

Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP

Leeona Galligan, Daniel B. Longley, Miranda McEwan, Timothy R. Wilson, Kirsty McLaughlin, and Patrick G. Johnston
Mol Cancer Ther 2005 4: 2026-2036 doi: 10.1158/1535-7163.MCT-05-0262 [Abstract] [Full Text] [PDF]  

Anti-CD70 antibodies: a potential treatment for EBV⁺ CD70-expressing lymphomas

Bruce F. Israel, Margaret Gulley, Sandra Elmore, Silvano Ferrini, Wen-hai Feng, and Shannon C. Kenney
Mol Cancer Ther 2005 4: 2037-2044 doi: 10.1158/1535-7163.MCT-05-0253 [Abstract] [Full Text] [PDF]  

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