Articles:

A role for PKC in potentiation of the topoisomerase II activity and etoposide cytotoxicity by wortmannin

Caroline Reis, Nicole Giocanti, Christophe Hennequin, Frédérique Mégnin-Chanet, Marie Fernet, Rodolphe Filomenko, Ali Bettaieb, Eric Solary, and Vincent Favaudon
Mol Cancer Ther 2005 4: 1457-1464. [Abstract] [Full Text] [PDF]  

Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1 and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells

Qunzhou Zhang, Xudong Tang, Qing Yi Lu, Zuo Feng Zhang, Jimmy Brown, and Anh D. Le
Mol Cancer Ther 2005 4: 1465-1474. [Abstract] [Full Text] [PDF]  

Sulindac sulfide–induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2

Frank A. Sinicrope and Robert C. Penington
Mol Cancer Ther 2005 4: 1475-1483. [Abstract] [Full Text] [PDF]  

Down-regulation of DNA mismatch repair proteins in human and murine tumor spheroids: implications for multicellular resistance to alkylating agents

Giulio Francia, Shane K. Green, Guido Bocci, Shan Man, Urban Emmenegger, John M.L. Ebos, Adina Weinerman, Yuval Shaked, and Robert S. Kerbel
Mol Cancer Ther 2005 4: 1484-1494. [Abstract] [Full Text] [PDF]  

Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells

David L. Morse, Heather Gray, Claire M. Payne, and Robert J. Gillies
Mol Cancer Ther 2005 4: 1495-1504. [Abstract] [Full Text] [PDF]  

Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer

Curtis Balch, Pearlly Yan, Teresa Craft, Suzanne Young, David G. Skalnik, Tim H-M. Huang, and Kenneth P. Nephew
Mol Cancer Ther 2005 4: 1505-1514. [Abstract] [Full Text] [PDF]  

Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine

Jody C. Chuang, Christine B. Yoo, Jennifer M. Kwan, Tony W.H. Li, Gangning Liang, Allen S. Yang, and Peter A. Jones
Mol Cancer Ther 2005 4: 1515-1520. [Abstract] [Full Text] [PDF]  

Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

Lindsay Stimson, Martin G. Rowlands, Yvette M. Newbatt, Nicola F. Smith, Florence I. Raynaud, Paul Rogers, Vassilios Bavetsias, Stephen Gorsuch, Michael Jarman, Andrew Bannister, Tony Kouzarides, Edward McDonald, Paul Workman, and G. Wynne Aherne
Mol Cancer Ther 2005 4: 1521-1532. [Abstract] [Full Text] [PDF]  

Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade

Yijiang Shi, Huajun Yan, Patrick Frost, Joseph Gera, and Alan Lichtenstein
Mol Cancer Ther 2005 4: 1533-1540. [Abstract] [Full Text] [PDF]  

Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein

Kara R. Jones, David A. Gewirtz, Steven M. Yannone, Shaoming Zhou, David G. Schatz, Kristoffer Valerie, and Lawrence F. Povirk
Mol Cancer Ther 2005 4: 1541-1547. [Abstract] [Full Text] [PDF]  

Counteracting tumor radioresistance by targeting DNA repair

Dörthe Schaue and William H. McBride
Mol Cancer Ther 2005 4: 1548-1550. [Full Text] [PDF]  

Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1

Yuseok Moon, Frank G. Bottone, Jr., Michael F. McEntee, and Thomas E. Eling
Mol Cancer Ther 2005 4: 1551-1558. [Abstract] [Full Text] [PDF]  

Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells

Anders Wallqvist, Ruili Huang, David G. Covell, Anna V. Roschke, Kristen S. Gelhaus, and Ilan R. Kirsch
Mol Cancer Ther 2005 4: 1559-1568. [Abstract] [Full Text] [PDF] Supplementary Data  

The anticancer activity of the fungal metabolite terrecyclic acid A is associated with modulation of multiple cellular stress response pathways

Thomas J. Turbyville, E.M. Kithsiri Wijeratne, Luke Whitesell, and A.A. Leslie Gunatilaka
Mol Cancer Ther 2005 4: 1569-1576. [Abstract] [Full Text] [PDF]  

Knockdown of c-Met by adenovirus-delivered small interfering RNA inhibits hepatocellular carcinoma growth in vitro and in vivo

Sheng-Zhou Zhang, Fei-Yan Pan, Jian-Feng Xu, Jun Yuan, Shi-Ying Guo, Gu Dai, Bin Xue, Wei-Gan Shen, Chuan-Jun Wen, Dong-Hong Zhao, and Chao-Jun Li
Mol Cancer Ther 2005 4: 1577-1584. [Abstract] [Full Text] [PDF]  

Role of p21^waf1/cip1 in effects of oxaliplatin in colorectal cancer cells

Taishi Hata, Hirofumi Yamamoto, Chew Yee Ngan, Minoru Koi, Akimitsu Takagi, Bazarragchaa Damdinsuren, Masayoshi Yasui, Yujiro Fujie, Takeshi Matsuzaki, Hiromichi Hemmi, Xundi Xu, Kotaro Kitani, Yosuke Seki, Ichiro Takemasa, Masataka Ikeda, Mitsugu Sekimoto, Nariaki Matsuura, and Morito Monden
Mol Cancer Ther 2005 4: 1585-1594. [Abstract] [Full Text] [PDF]  

Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells

Roohangiz Safaei, Barrett J. Larson, Timothy C. Cheng, Michael A. Gibson, Shinji Otani, Wiltrud Naerdemann, and Stephen B. Howell
Mol Cancer Ther 2005 4: 1595-1604. [Abstract] [Full Text] [PDF]  

Genome-wide transcriptional analysis of carboplatin response in chemosensitive and chemoresistant ovarian cancer cells

David Peters, John Freund, and Robert L. Ochs
Mol Cancer Ther 2005 4: 1605-1616. [Abstract] [Full Text] [PDF]  

WMC-79, a potent agent against colon cancers, induces apoptosis through a p53-dependent pathway

Teresa Kosakowska-Cholody, W. Marek Cholody, Anne Monks, Barbara A. Woynarowska, and Christopher J. Michejda
Mol Cancer Ther 2005 4: 1617-1627. [Abstract] [Full Text] [PDF]  

YC-1 suppresses constitutive nuclear factor-B activation and induces apoptosis in human prostate cancer cells

Yao-Ting Huang, Shiow-Lin Pan, Jih-Hwa Guh, Ya-Ling Chang, Fang-Yu Lee, Sheng-Chu Kuo, and Che-Ming Teng
Mol Cancer Ther 2005 4: 1628-1635. [Abstract] [Full Text] [PDF]  

Minireview:

Using bioinformatics and genome analysis for new therapeutic interventions

David W. Mount and Ritu Pandey
Mol Cancer Ther 2005 4: 1636-1643. [Abstract] [Full Text] [PDF]  

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