Articles:

Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma

Risa Torkin, Jean-François Lavoie, David R. Kaplan, and Herman Yeger
Mol Cancer Ther 2005 4: 1-11. [Abstract] [Full Text] [PDF]  

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X_L [(–)-gossypol] against diffuse large cell lymphoma

Ramzi M. Mohammad, Shaomeng Wang, Amro Aboukameel, Ben Chen, Xihan Wu, Jianyong Chen, and Ayad Al-Katib
Mol Cancer Ther 2005 4: 13-21. [Abstract] [Full Text] [PDF]  

(–)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X_L-mediated apoptosis resistance

Christopher L. Oliver, Michelle B. Miranda, Sanjeev Shangary, Stephanie Land, Shaomeng Wang, and Daniel E. Johnson
Mol Cancer Ther 2005 4: 23-31. [Abstract] [Full Text] [PDF]  

The nuclear factor B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)–induced apoptosis in antiestrogen-resistant breast cancer cells

Rebecca B. Riggins, Alan Zwart, Ruchi Nehra, and Robert Clarke
Mol Cancer Ther 2005 4: 33-41. [Abstract] [Full Text] [PDF]  

Up-regulation of c-Jun-NH₂-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by -tocopheryl succinate in human prostate cancer cells

Ke Zu, Lesleyann Hawthorn, and Clement Ip
Mol Cancer Ther 2005 4: 43-50. [Abstract] [Full Text] [PDF]  

Selective inhibitors of MEK1/ERK^44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells

Yunjie Sun and Frank A. Sinicrope
Mol Cancer Ther 2005 4: 51-59. [Abstract] [Full Text] [PDF]  

Epigenetic regulation of O⁶-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins

Rebecca P. Danam, Sherie R. Howell, Thomas P. Brent, and Linda C. Harris
Mol Cancer Ther 2005 4: 61-69. [Abstract] [Full Text] [PDF]  

Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: Unique consequences of a novel DNA-bonding mechanism

Marie-Hélène David-Cordonnier, William Laine, Amélie Lansiaux, Frédéric Rosu, Pierre Colson, Edwin de Pauw, Sylvie Michel, Francois Tillequin, Michel Koch, John A. Hickman, Alain Pierré, and Christian Bailly
Mol Cancer Ther 2005 4: 71-80. [Abstract] [Full Text] [PDF]  

Epigallocatechin-3-gallate induces apoptosis in estrogen receptor–negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation

Anshu M. Roy, Manjeshwar S. Baliga, and Santosh K. Katiyar
Mol Cancer Ther 2005 4: 81-90. [Abstract] [Full Text] [PDF]  

Anti-4 integrin monoclonal antibody inhibits multiple myeloma growth in a murine model

Dian L. Olson, Linda C. Burkly, Diane R. Leone, Brian M. Dolinski, and Roy R. Lobb
Mol Cancer Ther 2005 4: 91-99. [Abstract] [Full Text] [PDF]  

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition

Ranjit K. Goudar, Qing Shi, Mark D. Hjelmeland, Stephen T. Keir, Roger E. McLendon, Carol J. Wikstrand, Elizabeth D. Reese, Charles A. Conrad, Peter Traxler, Heidi A. Lane, David A. Reardon, Webster K. Cavenee, Xiao-Fan Wang, Darell D. Bigner, Henry S. Friedman, and Jeremy N. Rich
Mol Cancer Ther 2005 4: 101-112. [Abstract] [Full Text] [PDF]  

Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells

Józefa Wesierska-Gadek, Marieta Gueorguieva, and Marcel Horky
Mol Cancer Ther 2005 4: 113-124. [Abstract] [Full Text] [PDF]  

Metabolism and pharmacokinetics of the cyclin-dependent kinase inhibitor R-roscovitine in the mouse

Bernard P. Nutley, Florence I. Raynaud, Stuart C. Wilson, Peter M. Fischer, Angela Hayes, Phyllis M. Goddard, Steven J. McClue, Michael Jarman, David P. Lane, and Paul Workman
Mol Cancer Ther 2005 4: 125-139. [Abstract] [Full Text] [PDF]  

Role of phorbol ester localization in determining protein kinase C or RasGRP3 translocation: Real-time analysis using fluorescent ligands and proteins

Derek C. Braun, Yeyu Cao, Shaomeng Wang, Susan H. Garfield, Gang Min Hur, and Peter M. Blumberg
Mol Cancer Ther 2005 4: 141-150. [Abstract] [Full Text] [PDF]  

Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM

Michael Becker, Anette Sommer, Jörn R. Krätzschmar, Henrik Seidel, Hans-Dieter Pohlenz, and Iduna Fichtner
Mol Cancer Ther 2005 4: 151-170. [Abstract] [Full Text] [PDF]  

A therapeutic model for advanced endometrial cancer: Systemic progestin in combination with local adenoviral-mediated progesterone receptor expression

Donghai Dai, Lina Albitar, Tan Nguyen, Laura L. Laidler, Meenakshi Singh, and Kimberly K. Leslie
Mol Cancer Ther 2005 4: 169-175. [Abstract] [Full Text] [PDF]  

Carotenoids activate the antioxidant response element transcription system

Anat Ben-Dor, Michael Steiner, Larisa Gheber, Michael Danilenko, Noga Dubi, Karin Linnewiel, Anat Zick, Yoav Sharoni, and Joseph Levy
Mol Cancer Ther 2005 4: 177-186. [Abstract] [Full Text] [PDF]  

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