Molecular Cancer Therapeutics Targeting the PI3-Kinase Pathway in Cancer
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Contents: September 1 2004, Volume 3, Issue 9   [Index by Author] 
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Articles:

ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer
Marya F. McCarty, Jane Wey, Oliver Stoeltzing, Wenbiao Liu, Fan Fan, Corazon Bucana, Paul F. Mansfield, Anderson J. Ryan, and Lee M. Ellis
Mol Cancer Ther 2004 3: 1041-1048. [Abstract] [Full Text] [PDF]  

Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease
Sukhdev S. Brar, Claude Grigg, Kimberly S. Wilson, Walter D. Holder, Jr., Didier Dreau, Catherine Austin, Mareva Foster, Andrew J. Ghio, A. Richard Whorton, Grayson W. Stowell, Linda B. Whittall, Robert R. Whittle, David P. White, and Thomas P. Kennedy
Mol Cancer Ther 2004 3: 1049-1060. [Abstract] [Full Text] [PDF]  

Biological evaluation of cryptophycin 52 fragment A analogues: Effect of the multidrug resistance ATP binding cassette transporters on antitumor activity
Rima S. Al-awar, Thomas H. Corbett, James E. Ray, Lisa Polin, Joseph H. Kennedy, Margaret M. Wagner, and Daniel C. Williams
Mol Cancer Ther 2004 3: 1061-1067. [Abstract] [Full Text] [PDF]  

Structure-based design of a selective heparanase inhibitor as an antimetastatic agent
Keisuke Ishida, Go Hirai, Koji Murakami, Takayuki Teruya, Siro Simizu, Mikiko Sodeoka, and Hiroyuki Osada
Mol Cancer Ther 2004 3: 1069-1077. [Abstract] [Full Text] [PDF]  

In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities
Salvatore DeBonis, Dimitrios A. Skoufias, Luc Lebeau, Roman Lopez, Gautier Robin, Robert L. Margolis, Richard H. Wade, and Frank Kozielski
Mol Cancer Ther 2004 3: 1079-1090. [Abstract] [Full Text] [PDF]  

Gene expression changes induced by green tea polyphenol (–)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray
Ragini Vittal, Zachariah E. Selvanayagam, Yi Sun, Jungil Hong, Fang Liu, Khew-Voon Chin, and Chung S. Yang
Mol Cancer Ther 2004 3: 1091-1099. [Abstract] [Full Text] [PDF]  

Effect of curcumin on normal and tumor cells: Role of glutathione and bcl-2
Christine Syng-ai, A. Leela Kumari, and Ashok Khar
Mol Cancer Ther 2004 3: 1101-1108. [Abstract] [Full Text] [PDF]  

Differential sensitivity of cancer cells to docosahexaenoic acid–induced cytotoxicity: The potential importance of down-regulation of superoxide dismutase 1 expression
Wei-Qun Ding, Joshua L. Vaught, Hanako Yamauchi, and Stuart E. Lind
Mol Cancer Ther 2004 3: 1109-1117. [Abstract] [Full Text] [PDF]  

Gefitinib reverses breast cancer resistance protein–mediated drug resistance
Kae Yanase, Satomi Tsukahara, Sakiyo Asada, Etsuko Ishikawa, Yasuo Imai, and Yoshikazu Sugimoto
Mol Cancer Ther 2004 3: 1119-1125. [Abstract] [Full Text] [PDF]  

Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations
Manny D. Bacolod, Stewart P. Johnson, Anthony E. Pegg, M. Eileen Dolan, Robert C. Moschel, Nancy S. Bullock, Qingming Fang, O. Michael Colvin, Paul Modrich, Darell D. Bigner, and Henry S. Friedman
Mol Cancer Ther 2004 3: 1127-1135. [Abstract] [Full Text] [PDF]  

Neuronal-associated microtubule proteins class III ß-tubulin and MAP2c in neuroblastoma: Role in resistance to microtubule-targeted drugs
Sima Don, Nicole M. Verrills, Tracy Y.E. Liaw, Marjorie L.M. Liu, Murray D. Norris, Michelle Haber, and Maria Kavallaris
Mol Cancer Ther 2004 3: 1137-1146. [Abstract] [Full Text] [PDF]  

CHK1 and CHK2 are differentially involved in mismatch repair–mediated 6-thioguanine-induced cell cycle checkpoint responses
Tao Yan, Anand B. Desai, James W. Jacobberger, R. Michael Sramkoski, Tamalette Loh, and Timothy J. Kinsella
Mol Cancer Ther 2004 3: 1147-1157. [Abstract] [Full Text] [PDF]  

Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension
Hemant K. Roy, Patrick Iversen, John Hart, Yang Liu, Jennifer L. Koetsier, Young Kim, Dhanajay P. Kunte, Madhavi Madugula, Vadim Backman, and Ramesh K. Wali
Mol Cancer Ther 2004 3: 1159-1165. [Abstract] [Full Text] [PDF]  

Chemoinducible gene therapy: A strategy to enhance doxorubicin antitumor activity
Carlos A. Lopez, Eric T. Kimchi, Helena J. Mauceri, James O. Park, Neil Mehta, Kevin T. Murphy, Michael A. Beckett, Samuel Hellman, Mitchell C. Posner, Donald W. Kufe, and Ralph R. Weichselbaum
Mol Cancer Ther 2004 3: 1167-1175. [Abstract] [Full Text] [PDF]  

Muscle-targeted interleukin-12 gene therapy of orthotopic hepatocellular carcinoma in mice using in vivo electrosonoporation
Yo-ichi Yamashita, Mitsuo Shimada, Ryosuke Minagawa, Eiji Tsujita, Norifumi Harimoto, Shinji Tanaka, Ken Shirabe, Jun-ichi Miyazaki, and Yoshihiko Maehara
Mol Cancer Ther 2004 3: 1177-1182. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cell Growth & Differentiation
Copyright © 2004 by the American Association for Cancer Research.