Articles:

Henrik Lövborg, Peter Nygren, and Rolf Larsson

Multiparametric evaluation of apoptosis: Effects of standard cytotoxic agents and the cyanoguanidine CHS 828
Mol Cancer Ther 2004 3: 521-526. [Abstract] [Full Text] [PDF]  

G. Sakuntala Warshamana-Greene, Julie Litz, Elisabeth Buchdunger, Francesco Hofmann, Carlos García-Echeverría, and Geoffrey W. Krystal

The insulin-like growth factor-I (IGF-I) receptor kinase inhibitor NVP-ADW742, in combination with STI571, delineates a spectrum of dependence of small cell lung cancer on IGF-I and stem cell factor signaling
Mol Cancer Ther 2004 3: 527-536. [Abstract] [Full Text] [PDF]  

Elvira Crescenzi, Linda Varriale, Mariangela Iovino, Angela Chiaviello, Bianca Maria Veneziani, and Giuseppe Palumbo

Photodynamic therapy with indocyanine green complements and enhances low-dose cisplatin cytotoxicity in MCF-7 breast cancer cells
Mol Cancer Ther 2004 3: 537-544. [Abstract] [Full Text] [PDF]  

Mustafa K. Ozvaran, Xiaobo X. Cao, Steven D. Miller, Brett A. Monia, Waun Ki Hong, and W. Roy Smythe

Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma
Mol Cancer Ther 2004 3: 545-550. [Abstract] [Full Text] [PDF]  

Edward G. Mimnaugh, Wanping Xu, Michele Vos, Xitong Yuan, Jennifer S. Isaacs, Kheem S. Bisht, David Gius, and Len Neckers

Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity
Mol Cancer Ther 2004 3: 551-566. [Abstract] [Full Text] [PDF]  

Dong Xiao, Candace S. Johnson, Donald L. Trump, and Shivendra V. Singh

Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G₂-M-phase cell cycle arrest in PC-3 human prostate cancer cells
Mol Cancer Ther 2004 3: 567-576. [Abstract] [Full Text] [PDF]  

Lan Chun Tu, Thomas Melendy, and Terry A. Beerman

DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic
Mol Cancer Ther 2004 3: 577-586. [Abstract] [Full Text] [PDF]  

James A. Mobley, James O. L'Esperance, Mengchu Wu, Carolyn J. Friel, Robert H. Hanson, and Shuk-Mei Ho

The novel estrogen 17-20Z-21-[(4-amino)phenyl]-19-norpregna-1,3,5(10),20-tetraene-3,17ß-diol induces apoptosis in prostate cancer cell lines at nanomolar concentrations in vitro
Mol Cancer Ther 2004 3: 587-596. [Abstract] [Full Text] [PDF]  

Shawn E. Lupold and Ronald Rodriguez

Disulfide-constrained peptides that bind to the extracellular portion of the prostate-specific membrane antigen
Mol Cancer Ther 2004 3: 597-603. [Abstract] [Full Text] [PDF]  

Sung Dae Cho, Cheng Jiang, Barbara Malewicz, Yan Dong, Charles Y.F. Young, Kyung-Sun Kang, Yong-Soon Lee, Clement Ip, and Junxuan Lü

Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription
Mol Cancer Ther 2004 3: 605-612. [Abstract] [Full Text] [PDF]  

Shaochun Bai and David W. Goodrich

Different DNA lesions trigger distinct cell death responses in HCT116 colon carcinoma cells
Mol Cancer Ther 2004 3: 613-620. [Abstract] [Full Text] [PDF]  

Wai Yi Siu, Anita Lau, Talha Arooz, Jeremy P.H. Chow, Horace T.B. Ho, and Randy Y.C. Poon

Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated–dependent and –independent mechanisms
Mol Cancer Ther 2004 3: 621-632. [Abstract] [Full Text] [PDF]  

Valerie Gouazé, Jing Y. Yu, Richard J. Bleicher, Tie-Yan Han, Yong-Yu Liu, Hongtao Wang, Michael M. Gottesman, Arie Bitterman, Armando E. Giuliano, and Myles C. Cabot

Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy
Mol Cancer Ther 2004 3: 633-640. [Abstract] [Full Text] [PDF]  

Phillip J. Gray, Jr, David J. Bearss, Haiyong Han, Raymond Nagle, Ming-Sound Tsao, Nicholas Dean, and Daniel D. Von Hoff

Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer
Mol Cancer Ther 2004 3: 641-646. [Abstract] [Full Text] [PDF]  

Minireview:

Garth Powis and Lynn Kirkpatrick

Hypoxia inducible factor-1 as a cancer drug target
Mol Cancer Ther 2004 3: 647-654. [Abstract] [Full Text] [PDF]  

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