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All cDNA microarray studies were performed by the Microarray Core Facility at the Arizona Cancer Center. Probe preparation, microarray fabrication, and target preparation were performed as described in Watts et al. [J. Pharmacol. Exp. Ther., 299: 434–441, 2001] with the following modifications: polyA⁺ RNA from TMPyP2- or TMPyP4-treated and untreated HeLa S3 cells was labeled with Cy5-dCTP and that from untreated cells with Cy3-dCTP. Hybridizations were performed in duplicate for each timepoint (12, 24, 36, and 48 h).

The omitted reference is:

Watts, G., Futscher, B. W., Issett, R., Gleason-Guzman, M., Kunkel, M. W., and Salmon, S. E. cDNA microarray analysis of multidrug resistance: doxorubicin selection produces multiple defects in apoptosis signaling pathways. J. Pharmacol. Exp. Ther., 299: 434–441, 2001.

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